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Menadione is a fat-soluble vitamin. vitamin K is needed by the body in the process of blood clotting normally. Vitamin K is needed by the body in very small amounts and are usually already can be fulfilled in the food we eat so it does not need the K vitamin supplements. Vitamin K indicates a group of lipophilic, hydrophobic vitamins that are needed for the posttranslational modification of certain proteins, mostly required for blood clotting.
Vitamin K 1 also known as phylloquinone or phytomenadione (also called phytonadione). Vitamin K 2 (menaquinone, menatetrenone) is normally produced by bacteria in the large intestine, and food deficiency is extremely rare unless the intestines were severely damaged, incapable of absorbing molecules, or due to the declining production by normal flora, as seen in broad spectrum antibiotic use.
There are three synthetic forms of vitamin K, vitamin K 3, K 4 and K 5, which is used in various fields including the pet food industry (vitamin K 3) and to inhibit fungal growth (vitamin K 5). Vitamin K is involved in the process of blood clotting and also plays an important role in the process of bone formation, along with calcium and vitamin d. vitamin K deficiency can cause impaired blood clotting causing bleeding which is difficult to freeze.
The newborn is very easy to experience bleeding because the digestive system newborns still sterile and contain no bacteria can synthesize vitamin K while breast milk contains only a small amount of vitamin K. For that baby was given a number of vitamin K at birth to prevent a deficiency of vitamin K, Although allergic reactions from supplements is possible, there is no known toxicity associated with high doses of the phylloquinone (vitamin K 1) or menaquinone (vitamin K 2) form of vitamin K and therefore not tolerable intake level has been set.
However, the synthetic form of vitamin K, vitamin K3 (menadione), was proven to be toxic. In fact, a synthetic form of the vitamin from the over-the-counter supplement because large doses has been shown to cause allergic reactions, hemolytic anemia, and sitotoksisitas in liver cells. Vitamin K is found in various foods include leafy green vegetables, meats, and dairy products. Menadione can also be derived from the bacteria in the gut that synthesize vitamin K which is then absorbed and stored in the liver.
Vitamin K deficiency is rare but if there is a deficiency of vitamin K then it can cause problems with blood clotting and bleeding. The doctor will probably prescribe vitamin K if this happens. Vitamin K is also often given routinely to newborns to prevent bleeding.
Toxicity of menadione is going on except for those with excess consumption of vitamin K supplements. Poisoning symptoms of vitamin K can be either hemolysis of red blood cells, jaundice and brain damage. As with all individual needs and concerns about potential benefits from vitamin supplements, vitamin K best of answers obtained from a physician or medical professional familiar with the circumstances of individual patients.